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The symptoms of heartburn and heart attack are often confused17,but they are very different conditions. It’s important to learn the difference and know when to seek medical help.

Flaming heart

Signs Of A Heartburn

Signs of heartburn include a burning pain in your chest that rises toward your throat, burning pain that worsens when you bend over or lie down, or an unpleasant, acidic taste in your mouth and even bad breath3.

Heart attack

Signs Of A Heart Attack

Signs of a heart attack include chest discomfort, pain or discomfort in one or both arms, the back, the neck, the jaw or the stomach, shortness of breath, cold sweats, nausea or lightheadedness.

Most heart attacks involve discomfort in the center of the chest that lasts more than a few minutes, or that goes away and comes back. It can feel like uncomfortable pressure, squeezing, fullness or pain.

If your heartburn seems worse or different than usual, seek medical attention immediately if you experience chest discomfort, have heart disease or diabetes, smoke, are overweight or have high cholesterol. Do not wait. Call 911 immediately for emergency medical help.18




∆2018 IQVIA ProVoice Survey for OTC PPIs.
†Among OTC Frequent Heartburn Brands. IMS OTC Global Analysis 2017


3. Heartburn: Symptoms & causes. Mayo Clinic. (2018). Retrieved from
16. Heartburn: Overview. Cleveland Clinic. (2015). Retrieved from
17. Heartburn vs. heart attack. Harvard Health Publishing. Harvard Heart Newsletter. (2018). Retrieved from
18. Heartburn or heart attack: When to worry. Mayo Clinic. (2017). Retrieved from

Content sourced from the American Heart Association. The content above is for information purposes only. The third-party trademark/company identified above has not sponsored, approved or endorsed this product and is in no way affiliated with Pfizer or Nexium 24HR.